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Automated fluorine radiolabelling moves closer to the clinic

New technique could improve tumour diagnosis and treatment

A new automated fluorine-18 labelling procedure could make this useful radioisotope easier to use in medical imaging. 

Positron emission tomography (PET) is a nuclear medicine technique that provides a non-invasive way to diagnose and design treatment for tumours. The technique monitors how positron-emitting radionuclides bound to biological targeting molecules accumulate in the body. The radionuclide accumulates in cancerous tissue, and its concentration provides both qualitative and quantitative information about the tumour. Read more.

Patients ‘relieved’ by amyloid scans

But some come away with exaggerated ideas about the test’s value

Most patients said they were “relieved” by the results of their amyloid scans, but there’s still room for education as to what those results actually mean, researchers found in a small study.

In a single-center study at a tertiary care center staffed with experienced dementia specialists, the majority of 20 patient-caregiver pairs undergoing amyloid PET imaging said they felt relief from the scans, whether they were positive or negative, Joshua Grill, PhD, of the University of California Irvine, and colleagues reported in Alzheimer’s & Dementia. Read more.

Making this simple change to your diet could cut risk of Alzheimer’s disease

Researchers at the University of California looked at people with early memory decline and found that eating one particular fruit, twice a day, could have huge benefits

Eating a handful of grapes twice a day could stave off the ravages of Alzheimer’s disease and boost memory, new research claims. Scientists discovered that grapes protected against decline in Alzheimer-related areas of the brain. The study of people with early memory decline also discovered that grapes boosted attention and working memory performance. Low metabolic activity in these areas of the brain is a hallmark of early stage Alzheimer’s disease. The pilot study, carried out by the University of California - Los Angeles, found that there was significant change within six months of eating grapes twice a day. Read more.

Inflammation of heart muscle in sarcoidosis negatively affects coronary circulation

Inflammation of the heart muscle caused by sarcoidosis is associated with abnormal circulation in the arteries surrounding and supplying blood to the heart, according to a study published in the Journal of the American College of Cardiology: Cardiovascular Imaging.

The study, “Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis,” shows the direct negative effect of inflammation on coronary circulation in sarcoidosis patients, and underscores the fact that drugs that suppress the immune system and reduce inflammation of the heart muscle increase the widening capacity of the blood vessels of the heart. Read more.

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