N-Boc-trans-4-tosyloxy-L-proline methyl ester (5 mg)

Precursor for cis-4-[18F]Fluoro-L-proline
Product No.: NOL-95-0005

N-Boc-trans-4-tosyloxy-L-proline methyl ester
Product No.:NOL-95
CAS No.:88043-21-4

Product Name:  N-Boc-trans-4-tosyloxy-L-proline methyl ester
Synonyms:  N-(tert-Butoxycarbonyl)-trans-4-(p-toluenesulfonyl-oxy)-D-proline Methyl Ester ;1,2-pyridinedicarboxylic acid, 4-[[(4-methylphenyl)-sulfonyl]oxyl]-1- (1,1-dimethylethyl)-2-methyl ester, (2S, trans)
CAS No.:  88043-21-4
Molecular Formula:  C18H25NO7S
Molecular Weight:  399.46
Application:  Precursor for cis-4-[18F]Fluoro-L-proline
Presentation:  Packaged in amber vials or amber screw-cap vials with teflon-coated stoppers under argon atmosphere

Storage and Stability

  • Store the product at -20 ºC, protected from light.
  • Short-term storage at higher temperatures does not affect product quality.


  • Complete documentation - Certificates of Analysis including testing reports of 1H-NMR and HPLC spectra for each shipment
  • Customized dispensing available


  • Hamacher K. et al. [18F]fluoroproline: A potential tracer for collagen synthesis. Radiosynthesis and biological evaluation. 43rd Annual Meeting of the Society of Nuclear Medicine, Denver, Colorado, USA, June 3-5, 1996. J. Nucl. Med. 1996, 37, 41P.
  • Jones H. A. et al. External monitoring of 18F-fluoroproline uptake in a rabbit model of pulmonary fibrosis. Annual Congress of the European Respiratory Society, Berlin, Germany, September 20-24, 1977, European Respiratory Journal Supplement. 1977, 10, 323S-324S.
  • Gupta N. C. et al. Feasibility study for PET imaging of pulmonary fibrosis with cis- 4-[18F]fluoro-L-proline (FP). J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario, Canada P116-P117.
  • Mazza S. M. A Semi-Automatic Synthesis of cis-4-[18F]fluoro-L-proline using the General Electric FDG Microlab. J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario, Canada P144.